Publication in Small
🚀 New Research Alert!
Our team is excited to share our latest publication in Small, where we introduce a novel barrier-free microfluidic device designed to study the tumor microenvironment in glioblastoma.
🧠 Key Findings:
✔️ Tumor-driven extracellular matrix stiffening boosts glioblastoma aggressiveness.
✔️ Stiffening also impairs immune cell infiltration, creating an additional challenge for the immune response.
✔️ The effect of temozolomide on immune infiltration is explored, offering insights for improved immunotherapies.
This work provides a new platform to investigate immune-tumor interactions in a physiologically relevant setting, contributing to the ongoing effort to improve glioblastoma prognosis in patients.
👏 Huge congratulations to Clara and Claudia for leading this study, and a big thank you to Vira and Mehran for their contribution, and to Sara, Ignacio, Rosa, and Manuel for their support.
📄 Read the full paper here: https://onlinelibrary.wiley.com/doi/10.1002/smll.202409229
TME Lab Research Group | Instituto de Investigación Sanitaria Aragón – IIS Aragón | Aragon Institute of Engineering Research (I3A) | Centro de Investigación Biomédica en Red CIBER | Universidad de Zaragoza | Beonchip
#CancerResearch #Microfluidics #Glioblastoma #OrganOnChip #Immunology #Small
Tissue Microenvironment lab - Universidad de Zaragoza | We are us and our circumstances (José Ortega y Gasset)
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