DISCOVER
TME LAB

The Tissue MicroEnvironment (TME)  is a highly multidisciplinary group made up of engineers, physicists, and researchers from various biomedical branches. This group has the general objective of understanding, simulating, and preserving the environment of cells and tissues in their pathophysiological conditions to find new therapeutic strategies and personalized solutions for patients.

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WHO WE ARE

TME Lab (Tissue MicroEnvironment Lab) is a research group at the University of Zaragoza, officially recognized as a consolidated group by the Government of Aragón. It is a multidisciplinary team composed of engineers, biologists, mathematicians, and physicists who develop, together, new ideas, methods, and applications in Biomedical Engineering.

We belong to the Aragón Institute of Engineering Research (I3A), to the Aragón Health Research Institute (IIS Aragón), and to the national Networking Research Center on Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN) as part of the group CB06/01/0069.

 

 

 

WHAT IS OUR AIM

Our main aim is to develop and apply multiapproach (in silico, in-vitro, and ex-vivo) models to better understand relevant biological processes, with special emphasis on the interaction between cells and their biophysical environment.

We are experts in developing biological models integrating the state of the art in mathematical simulation tools and microfluidic technology to mimic biological functions or diseases and monitor cells and tissues in biomimetic environments.

We are focused on reproducing physiological and pathological situations that allow us to deepen a better understanding of biological processes with important fundamental, industrial, or clinical impact.

 

 

ONCOLOGY MODELS

IN VITRO MODELS

CARDIOVASCULAR MODELS

MICROFLUIDICS

ORGAN ON CHIP

IN SILICO MODELS

WHAT WE DO

We try to cover all facets of a research group: fundamental research, translation to clinics, and technology transfer to industry and high-level training.

Our main difference is the seamless combination in most of our projects of physico-mathematical or data-driven models with biomimetic microfluidic based devices to build reliable, robust, easy-to-use and cost effective models of relevant biological problems which could impact the clinical practice and medical industry.

We develop our research under the umbrella of national and European projects in close collaborations with other national, international groups as well as companies and clinicians.

Our outcome is related to publications in high-impact journals, patents, and products and training of new PhDs. With this aim, we are a group always open to incorporate new talents, where they will find a very proactive group involved in ambitious projects.

 

PROJECTS

PATENTS

STUDENTS SUPERVISION

CONTRATS

SPIN-OFF

PUBLICATIONS

PROJECTS

Moore4Medical

Accelerate innovation in medical devices by “Moore for Medical” G.A. nº: 876190

BRAV3

Computational biomechanics and bioengineering 3D printing to develop a personalised regenerative biological ventricular assist device to provide lasting functional support to damaged hearts  (G.A. nº 874827) RIA – Research and Innovation action

 

PRIME

Advanced and versatile PRInting platform for the next generation of active Microfluidic dEvices (G.A. no. 829010). H2020-FETOPEN-2018-2019-2020-01

CISTEM

Heart on chip based on induced pluripotent stem cell technology for personalized medicine is a Horizon 2020 project; Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE). 

GBM_SIMUL

In vitro characterization and in vitro/in vivo simulation of the effect of hypoxia and drug dosis in glioblastoma growth.PGC2018-097257-B-C31


POSITION-II

POSITION-II has received funding within the Electronic Components and Systems for European Leadership Joint Undertaking (ECSEL JU) in collaboration with the European Union’s H2020 Framework Programme (H2020/2014-2020) and National Authorities, under grant agreement Ecsel-783132-Position-II-2017-IA

NEWS

11F 2021 Women and Girl in Science

Our team, made up mostly of women, is working daily to achieve scientific advances. We are proud to have such a wonderful team. Thank you girls !!! "I never see what has been done; I only see what remains to be done" - Marie Curie        

5th Anniversary BEOnCHIP

Founded in 2016, our SpinOff BEOnCHIP celebrates its fifth anniversary today. It is a great team dedicated to designing, manufacturing, and selling easy-to-use, disposable biomimetic cell culture devices. We wish you lots of success in the future!   Find out more...

World Cancer Day 2021

Today is World Cancer Day 2021 and as they say, SCIENCE has the key to this disease. Join the challenge: https: //www.miretocontraelcancer.aecc.es/reto/grullas-contra-el-cancer